Research

The Grady Trauma Project (GTP) is a large-scale study of the impacts of stress- and trauma-related risk factors for posttraumatic stress disorder (PTSD) and related behavioral and physical health comorbidities in a high risk, highly trauma exposed urban population of Black Americans in Atlanta, GA, USA.

This interdisciplinary team of investigators is led by Co-Directors Abigail Lott, PhD, ABPP (Director of Treatment Research and Education), Vasiliki Michopoulos, PhD (Director of Translational Neuroscience), and Jennifer Stevens, PhD (Director of Human Neuroscience).

The GTP leverages translational techniques, such as neuroimaging, physiology and psychophysiology, to study the underlying biology of adverse health outcomes related to trauma exposure and PTSD.  Over the last 15 years, the GTP has conducted trauma interviews on over 12,000 participants recruited from medical clinic waiting rooms at Grady Memorial Hospital in Atlanta, GA.

Data from GTP indicate high rates of trauma exposure, with >90% reporting at least one trauma, and 46% meeting lifetime diagnostic criteria for PTSD.

Current GTP studies are trying to 1) understand the mechanisms by which women are more at risk than men for PTSD and other stress- and trauma-related adverse health outcomes and co-morbidities (e.g. reproductive dysfunction, cardiovascular and metabolic disease, immune dysfunction, infectious disease, cancer and aging), 2) identify new neurobiological treatment targets following acute trauma exposure, 3), address intergenerational trauma-related risk and adverse outcomes, and 4) develop culturally informed evidence-based, accessible interventions for PTSD other stress- and trauma-related adverse health outcomes with the long term goal of reducing health inequities and improving health outcomes in Black communities.

Please look further at our various projects:

PTSD Intervention Studies

MPC.png

Primary Care-based Mindfulness Intervention for Chronically Traumatized Individuals

PI: Abigail Powers Lott, PhD, ABPP

DBT.png

Dialectical Behavior Therapy Skills Training for High-Risk African American Pregnant Women

PIs: Abigail Powers Lott, PhD, ABPP & Briana Woods-Jaeger, PhD

MINDLOGO.jpg

Mechanistic Interventions of Neuroscience of Dissociation (MIND) Study

PI: Negar Fani, PhD

SanneSeanTMS.png

TMS for PTSD study

PI: Sanne Van Rooij, PhD

Women's Health - Related Studies

E2_edited.jpg

Neuroendocrine risk factors for PTSD in women

PI: Jennifer Stevens, PhD

bumpp.png

Pregnancy and PTSD

PI: Vasiliki Michopoulos, PhD

Avon-Graphic-1024x585.png

PTSD Risk and Breast Cancer

PI: Jennifer Stevens, PhD

PTSD Studies

AURORA.png

The AURORA Study

PI: Jennifer Stevens, PhD

CP.png

Impact of Trauma Exposure on Critical Periods In Brain Development

PI: Jennifer Stevens, PhD

CP.png

Addressing ACEs among Hispanic Caregivers in a Pediatric Primary Care Population to Improve Child Health and Decrease Early Adversity

PI: Abigail Lott, PhD ABPP